Neomycin Sulfate, USP Grade

Gold Biotechnology, Inc SKU: N1058153-5
Neomycin Sulfate, USP Grade

Neomycin Sulfate, USP Grade

Gold Biotechnology, Inc SKU: N1058153-5
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Description

Neomycin is a broad-spectrum aminoglycoside antibiotic isolated from Streptomyces species. It targets gram-negative and gram-positive bacteria. Neomycin can also be used as a selection agent for prokaryotic cells transformed with the neo gene or NPT II resistance gene and to study toxic antibacterial side effects. In addition, neomycin is a calcium channel protein inhibitor and DNase I inhibitor. It can be used in a variety of cell culture applications.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

In addition to its use in antimicrobial susceptibility testing, neomycin sulfate is used for food testing in TSN agar to select for Clostridium perfringens. It inhibits growth of Enterobacteria and Clostridium bifermentans. Neomycin can be used to negatively select for plants transformed with plasmid containing Agrobacterium mediated transformation resistance and to cells containing pcDNA3 resistance plasmids.

Details

CAS NUMBER 1405-10-3
CHEMICAL GRADE
  • USP - United States Pharmacopeia Grade
EXTERNAL URL Click here
UNSPSC CODE 51101500
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